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穿戴式健行加速仪系统用于估计动脉硬度:试点研究
概括
一个新的可穿戴系统使用加速度计来测量动脉硬度,这是心血管健康的关键因素. 这项技术使得频繁的,无需操作者的监测,即使在运动引起的生理变化后.
科学领域:
- 生物医学工程 生物医学工程
- 心血管生理学心血管生理学
- 可穿戴技术可穿戴技术
背景情况:
- 动脉硬度对于预防心血管疾病至关重要.
- 目前的方法缺乏频繁,无操作员测量能力.
- 对于持续的动脉硬度评估存在技术差距.
研究的目的:
- 开发一种基于加速度计的可穿戴系统,用于估计局部动脉硬度指标.
- 通过患者特定的校准和运动后评估来验证系统的性能.
- 为了解决对动脉硬性的持续,无操作员监测的需求.
主要方法:
- 开发了一个可穿戴系统,使用加速度计数据来分析加速度囊图 (APG) 信号.
- 在APG信号特征上采用一点患者特定校准.
- 对12名受试者进行了体外研究,包括运动前后的测量.
- 确定了一个潜在的校准特征: (a-b) / ((a"-b").
主要成果:
- 获得的APG信号显示出高可靠性 (SNR>38dB) 和可重复性 (CoV <10%).
- 在运动后,局部度指标显著受到干扰 (p < 0.05).
- 估计的Ep与实际值有很强的相关性 (r = 0.761,p < 0.05).
- 估计的β (r = 0.682,p < 0.05) 和AC (r = 0.615,p < 0.05) 显示了中等的相关性.
结论:
- 开发的可穿戴系统可靠地估计了局部动脉硬度指标.
- 该系统可以准确地评估运动后的硬度,即使有生理干扰.
- 这项技术有可能在临床环境中持续,无操作员的动脉硬性监测.
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