相关实验视频

Updated: Jul 8, 2025

MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges

MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges

Published on: December 17, 2014

动态磁共振血管指纹在高头期间用于定量和多参数脑血管反应性测量

Gregory J Wheeler, Quimby N Lee, Audrey P Fan

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

|December 12, 2023

概括

磁共振血管指纹 (MRvF) 能够同时快速地绘制大脑血液体积,氧化和血管大小. 这种技术可以动态评估脑血管反应,为血管健康提供新的见解.

科学领域:

生物物理学的生物物理.
神经成像是一种神经成像.
医学物理医学物理

背景情况:

磁共振指纹 (MRF) 提供先进的MR图像分析.
MR血管指纹 (MRvF) 扩展了脑血管指标的MRF.
对大脑血液体积 (CBV),微血管半径和氧和 (SO2) 的定量测绘对于理解大脑功能至关重要.

研究的目的:

展示一种用于动态,同时获取MRvF和BOLD测量的新方案.
为了研究 CBV,半径和 SO2 的定量变化,以应对高皮刺激.
将MRvF衍生的脑血管反应 (CVR) 与传统的BOLD和ASL CVR方法进行比较.

主要方法:

使用快速,旋转和梯度回声脉冲序列进行动态MRvF和BOLD采集.
实施了一个量身定制的超 (5% CO2) 呼吸模式.
与BOLD和动脉旋转标签 (ASL) 的定量MRvF指标进行比较.

主要成果:

成功证明了动态,同时获得MRvF和BOLD措施.
展示了对二氧化碳刺激的量化CBV,半径和SO2的变化.
可以直接比较基于MRvF的CVR与传统的BOLD和ASLCVR.

结论:

新的协议允许对脑血管反应的快速,定量和多参数评估.
这种技术有助于进一步调查CVR的大小和速率.
开发功能性成像生物标志物用于阿尔茨海默氏症等脑血管疾病的潜力.

更多相关视频

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Published on: May 10, 2024

相关概念视频

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...