用于测量关节 - 关节脉冲波速率的结膜扫描仪自评测装置:试点可用性研究
概括
一种新的,价格实惠的光电吸收仪器准确地测量动脉硬度 (带-大腿脉冲波速率) 适用于家庭使用. 这种易于使用的技术在初级保健机构中显示出早期心血管风险检测的潜力.
科学领域:
- 心血管生理学心血管生理学
- 生物医学工程 生物医学工程
- 老年学是一门学科.
背景情况:
- 动脉硬是血管衰老的关键指标,可以预测心血管事件和死亡率.
- Carotid-femoral脉冲波速度 (cf-PWV) 是评估动脉硬性的黄金标准.
- 目前的cf-PWV测量设备昂贵,需要专家操作,不适合家庭护理.
研究的目的:
- 开发和评估一种新的,易于使用的,基于光斑质谱的自动化装置,用于测量cf-PWV.
- 与专家测量相比,评估自测设备的可用性和可重复性.
- 确定该设备在初级卫生和家庭护理环境中的潜力.
主要方法:
- 开发一个负担得起的,用于cf-PWV测量的自动化光电显微镜装置.
- 一个in-vivo研究涉及25名受试者,比较了自我执行和专家执行的测量.
- 通过用户体验评分进行可用性评估 (1-5级).
主要成果:
- 自主和专家进行的测量显示出强烈的相关性 (r=0.88) 和微不足道的偏差,表明高可重现性.
- 参与者报告了高可用性,平均得分为3.98±0.83,强调了易用性.
- 该设备的可行性和可靠性被证明是不经验丰富的操作员使用的.
结论:
- 这种新型的光多缩仪提供了一种可靠且易于使用的方法来测量动脉硬度 (cf-PWV).
- 这项技术有可能在非临床环境中促进早期心血管风险评估,例如家庭护理和初级卫生.
- 针对黄金标准设备的进一步临床验证正在进行中.
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