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Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
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Dementia01:30

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
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Cognitive learning is based on purposive behavior, incidental learning, and insight learning.
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相关实验视频

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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
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莱特:对于认知衰退的数字干预

Vasileios S Loukas, Thomas Kassiotis, Ignacio Lamata Martinez

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
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    莱特 (LETHE) 项目推出了一个新的平台,用于早期检测和预防高危老年人的认知衰退. 该系统使用大数据进行个性化干预,旨在通过改变生活方式来减缓痴呆症的进展.

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    科学领域:

    • 老年学是一门学科.
    • 神经科学是一个神经科学.
    • 数字健康数字健康

    背景情况:

    • 痴呆症是老年人残疾的主要原因,受病理,生活方式和遗传因素的影响.
    • 目前的痴呆症管理侧重于早期诊断和减缓由于缺乏治愈的进展.
    • 现有的辅助技术主要针对改善记忆和思维.

    研究的目的:

    • 介绍LETHE研究及其新的平台,用于预防从无症状到前发性痴呆的全谱的认知衰退.
    • 建立一个大数据收集和分析系统,用于个性化风险检测和干预.
    • 通过为期2年的临床试验来评估和验证LETHE系统和获得的知识.

    主要方法:

    • 开发一个大数据平台,用于认知衰退管理.
    • 实施一个整体的,多领域的生活方式干预试验.
    • 基于云计算的健康管理系统的建筑设计.

    主要成果:

    • 莱特 (LETHE) 平台允许针对认知衰退进行个性化风险检测和干预.
    • 该系统支持远程和持续监测患者健康状况.
    • 开发了认知衰退和干预坚持的预测模型.

    结论:

    • 莱特系统为认知健康的多领域生活方式干预提供了一种全新,整体的方法.
    • 它旨在通过预测分析实现及时的医疗决策,从而改善患者的治疗结果.
    • 该平台代表了健康管理系统和老年认知护理云开发的进步.