一个数字控制的集成电路解决方案用于耳治疗与电荷平衡
概括
一个用于治疗耳的新型集成电路直接向内耳产生精确的电刺激. 这种可植入芯片为潜在的治疗应用提供先进的波形生成和电荷平衡.
科学领域:
- 生物医学工程 生物医学工程
- 电气工程 电气工程
- 神经科学是一个神经科学.
背景情况:
- 耳是影响全球数百万人的普遍疾病,往往需要创新的治疗方法.
- 目前的耳治疗有局限性,导致需要先进的神经调节装置.
- 内耳的直接电刺激在声管理方面显示出有前途.
研究的目的:
- 描述了一种设计用于精确电刺激的新型集成电路,用于耳治疗.
- 详细介绍了用于内耳神经调节的可植入芯片的架构和功能.
- 提出一种高压,低功耗的解决方案,用于产生任意电流波形,用于治疗目的.
主要方法:
- 使用0.18um的BCD高压CMOS工艺制造一个集成电路.
- 关键组件的集成包括一个8位DAC,振幅控制,高压驱动和电荷平衡电路,电平变速器,SRAM,ROM和控制单元.
- 开发一个芯片上的控制单元,用于自主波形生成和刺激传递.
主要成果:
- 集成电路成功地产生了随意波形的电流刺激,直接进入内耳组织.
- 达到±0.1mV的精确电荷平衡,这对于安全有效的神经刺激至关重要.
- 消除了对外部控制电路的需求,使一个紧的,可植入的多芯片模块成为可能.
结论:
- 开发的集成电路代表了用于耳治疗的可植入神经调制装置的重大进步.
- 芯片的功能促进了精确的,按需的电刺激,为管理耳提供了新的途径.
- 这项技术有可能通过可定制的刺激参数来实现个性化的耳治疗.
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