基药物和水凝:一个有前途的抗瘤组合
Jiamin Yao1, Shaojuan Song1, Hang Zhao1
1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Drug delivery
|December 12, 2023
概括
基于的化疗药物会引起副作用. 水凝药物递送系统为增强的抗瘤疗法提供了更安全,更有针对性的方法,改善了癌症治疗结果.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 在瘤学瘤学.
背景情况:
- 基于的药物是用于瘤的标准第一线化疗.
- 免费的金药物会引起显著的全身副作用.
- 针对性的药物输送对于提高抗瘤疗效和安全至关重要.
研究的目的:
- 系统地审查用于癌症治疗的/水凝组合系统.
- 分析基于水凝的金药物输送的特性和优势.
- 为开发先进的水凝药物递送系统提供见解.
主要方法:
- 对/水凝系统现有研究的文献综述.
- 分析水凝作为药物载体的特性.
- 讨论通过水凝介导的制药物输送的好处.
主要成果:
- 水凝可以封装制药,形成有效的组合系统.
- 与免费药物相比,金/水凝系统显示出更好的抗瘤作用.
- 水凝载体增强药物向性,降低全身毒性.
结论:
- 基于水凝的输送系统代表了更安全,更有效的化疗的有希望的战略.
- 对/水凝系统的进一步研究可以优化癌症治疗策略.
- 本次审查巩固了当前的知识,指导了该领域的未来发展.
相关概念视频
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Targeted Cancer Therapies
7.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.6K
Drugs that Stabilize Microtubules
2.1K
Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...
2.1K


