对抗纹功能的研究和用Phaseolus angularisis改善奶油
Sarang Oh1,2, Jeehaeng Jeong2, Myeongju Kim1
1College of Life Science, Kyung Hee University, Yongin-si, Korea.
International journal of cosmetic science
|December 12, 2023
概括
在一项为期12周的临床试验中,Phaseolus angularis种子提取物 (PASE) 乳液显著减少了眼睛的纹,改善了皮肤的水分. 这种天然成分显示出作为一种安全,有效的抗衰老化品的承诺.
科学领域:
- 皮肤病学 皮肤病学
- 化品科学 化品科学
- 自然产品研究自然产品研究
背景情况:
- 长期暴露于紫外线 (UV) 辐射会加速皮肤衰老,导致纹和屏障破坏.
- 角 (Phaseolus angularis) 种子提取物 (PASE) 在试验室中证明了其在保护皮肤免受UVB引起的皮肤损伤方面的有效性.
- 以前的研究表明PASE在HaCaT细胞中的潜力,但缺乏对抗衰老作用的临床验证.
研究的目的:
- 为了临床评估Paseolus angularis种子提取物 (PASE) 奶油对人类眼睛纹的抗衰老功效.
- 评估PASE奶油对皮肤屏障功能,粗性和水分的影响.
- 在人类研究中确定PASE奶油的安全性和耐受性.
主要方法:
- 这是一项为期12周的单一集中,随机,双盲研究,涉及21名30-59岁的健康女性.
- PASE奶油应用于一个眼睛的纹区域,另一个是安慰剂,每天两次.
- 通过视觉评估,皮肤造型测量 (R1-R5参数) 和受试者问卷进行纹评估.
主要成果:
- 帕斯奶油显著降低了皮肤粗度参数 (R1,R4,R5) 的18.1%,18.6%和25.0%,分别.
- 与安慰剂相比,PASE奶油组的皮肤水分改善率大约是PASE奶油组的两倍.
- 在研究期间,没有参与者报告任何不良副作用.
结论:
- PASE奶油在减少眼睛纹和增强皮肤水分方面表现出临床显著的改善.
- 角 (Phaseolus angularis) 种子提取物是一种安全,天然的成分,有可能用于抗纹功能化品.
- 通过提供一个有前途的天然替代方案,以对抗紫外线暴露引起的皮肤衰老的影响.
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