肝移植患者的贫血:患病率,严重程度,危险因素和生存率
Nina Øksnes Hegland1, Omid Rezahosseini1, Christian Ross Pedersen2
1Department of Infectious Diseases, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
|December 12, 2023
概括
肝移植受体中贫血很常见,在移植前影响了69%. 然而,移植前的贫血在本研究中没有影响1年生存率.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 移植医学 移植医学
- 血液学 血液学 血液学
背景情况:
- 贫血是肝移植 (LTx) 接受者的常见并发症.
- 关于贫血的患病率,危险因素以及对LTx后生存的影响的数据有限.
研究的目的:
- 确定LTx.前后贫血的患病率和严重程度.
- 为了确定与LTx前贫血相关的风险因素.
- 评估前LTx贫血对1年生存率的影响.
主要方法:
- 使用移植知识中心数据库进行回顾性队列研究.
- 包括346名首次接受LTx的成年患者.
- 使用了后勤回归和卡普兰-梅尔分析.
主要成果:
- 贫血的患病率在LTx前为69%,在LTx后的一年为45%.
- 男性性别和较高的MELD得分与LTx前贫血有关.
- 发性肝衰竭与较低的前LTx贫血几率相关.
- 接受者患有 (93%) 和没有 (91%) 的LTx前贫血,1年生存率相似.
结论:
- 肝移植接受者中贫血的发生率很高.
- 移植前贫血与男性性别和MELD得分相关,但不会影响1年生存率.
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