对白风可见光疗法的专注审查
Mitchell J Winkie1,2, Goranit Sakunchotpanit1,3, Carlos E Salazar1,2
1Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Photodermatology, photoimmunology & photomedicine
|December 12, 2023
概括
可见光疗法,包括红色和蓝色光,对白风的再发色和脱色有希望,副作用很少. 需要进一步的研究来确认这种具有挑战性的疾病的疗效和长期结果.
科学领域:
- 皮肤病学 皮肤病学
- 照相医疗 (photomedicine) 是一种医学技术.
- 医学光学医学光学
背景情况:
- Vitiligo 带来了治疗挑战和不可预测的进展.
- 可见光光疗法在白风中提供了重颜色和脱颜色的潜力.
- 这种治疗与最小的不良事件有关.
研究的目的:
- 审查可见光治疗白风的机制性理解.
- 评估可见光疗法在白风管理中的临床结果.
- 综合目前关于白风红色和蓝色光的证据.
主要方法:
- 在PubMed上从1965年5月到2023年8月进行了系统的文献搜索.
- 496个独特的文章被检索并选出相关性.
- 包括的研究使用可见光 (380-750纳米) 进行白风复发或脱色,作为单疗法或组合疗法.
主要成果:
- 27篇文章符合纳入标准,提供临床前和临床数据.
- - (He-Ne) 激光 (红光) 和蓝色发光二极管 (LED) 已证明在白风复颜中具有有效性.
- 已确定Q开关红宝石和频率翻倍 (FD) Nd:YAG激光器是白风脱色的有效可见光选择.
结论:
- 可见光疗法在治疗白风方面显示出令人鼓舞的有效性,尽管研究存在局限性.
- 红光和蓝光疗法可以在最小的不良事件中刺激再发色.
- 特定的激光提供了可行的脱色选项,但需要进行更大规模的研究来验证疗效和长期结果.
相关概念视频
01:22Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K
01:14Changes in Skin Color: Clinical Perspectives
2.0K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K
01:02Ultraviolet and Visible (UV–Vis) Spectroscopy: Overview
2.7K
Ultraviolet–visible (UV–visible or UV–Vis) spectroscopy is an analytical technique that investigates the interaction between matter and UV–Vis light within the electromagnetic spectrum. This method is widely used for its versatility, simplicity, and relatively quick data acquisition, making it valuable for both qualitative and quantitative analysis. When UV–Vis radiation passes through a material, molecules absorb light depending on the energy required for...
2.7K
01:30Skin Cancer
4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K