水果,全谷物和总能量摄入量与肠道微生物群多样性和组成的关联
Yixiao Wang1, Keming Zhang2, Linna Dai1
1Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
饮食习惯会影响肠道细菌. 全谷物促进微生物多样性,而水果和能量摄入影响特定的细菌群体. 这些发现表明,饮食可以调节肠道微生物群,以改善健康.
科学领域:
- 微生物组研究的研究.
- 营养科学 营养科学
- 人类肠道生态学
背景情况:
- 饮食和肠道微生物组之间的复杂关系对人类健康至关重要.
- 特定的饮食成分,如水果,全谷物和总体能量摄入量,显著影响肠道微生物的组成.
- 了解这些饮食影响至关重要,特别是在像中国人这样的多元化人口中.
研究的目的:
- 调查水果,全谷物和总能耗以及肠道微生物群的多样性和组成之间的联系.
- 阐明特定的饮食模式如何影响肠道中关键细菌种群的丰富性.
- 提供有关调节肠道微生物组的潜在饮食干预措施的见解.
主要方法:
- 一项涉及167名年龄在40至75岁的中国成年人的横截面研究.
- 数据收集包括个人历史问卷,七天的饮食记录和便样本捐赠.
- 使用Illumina Novaseq分析肠道微生物组成的细菌16S rRNA基因测序 (V3-V4区域).
主要成果:
- 果实摄入量与特定细菌的丰富程度呈正相关,包括细菌和链球菌.
- 较高的全谷物消费与增加的肠道微生物多样性 (Shannon,Simpson,Chao1指数) 以及改变了Lachnospiraceae和Actinobacteria的丰富性有关.
- 增加的总能量摄入量与较少的无气体类型的丰度和较高的乳杆菌和Acidaminococcus的丰度有关.
结论:
- 全谷物消费与肠道微生物多样性有显著的积极关联.
- 水果和总能量摄入量与特定肠道细菌种群的丰富程度有关.
- 侧重于全谷物和水果的饮食干预措施可能有效调节肠道微生物群组成,以改善健康结果.
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