结肠直肠癌查高风险组的可修改风险因素:用倾向性得分方法进行横截面研究
Xuan Zhong1, Nongping Feng2, Binfa Ouyang1
1Department of Oncology, Injury and Nutrition, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, Guangdong Province, People's Republic of China.
Risk management and healthcare policy
|December 12, 2023
概括
深的结肠直肠癌 (CRC) 查发现,高危人群的高检测率为28.50%. 可改变的生活方式因素,如吸烟,饮食和肥胖,显著增加CRC风险,需要有针对性的干预措施.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 结肠直肠癌 (CRC) 的发病率和死亡率在全球范围内不断增加.
- 识别高风险人群对于有效的CRC预防和控制至关重要.
- 深面临着CRC日益严重的威胁,需要进行本地化风险评估.
研究的目的:
- 为了确定深大肠直肠癌高风险个体的检测率.
- 分析与高风险人群中CRC检测相关的可修改风险因素.
- 为深的CRC预防提供有针对性的公共卫生干预信息.
主要方法:
- 采用了多阶段分层集群采样方法,调查了深45-74岁的30921名居民.
- 横截面分析包括24,613名具有有效便隐性血液检测 (FOBT) 结果的参与者.
- 用逆概率治疗权重 (IPTW) 分析可修改的风险因素和CRC检测率的多项逻辑回归.
主要成果:
- 高风险结直肠癌 (CRC) 组的整体检测率为28.50%.
- 在男性,60岁以上的个人,拥有高等教育,其他婚姻状况和城市居民 (P <0.05) 中观察到更高的检测率.
- 吸烟,饮酒,肥胖,身体不活动,饮食不良 (水果/蔬菜摄入量低),红肉/加工肉类摄入量高,谷物食品摄入量为CRC的显著风险指标 (P<0.05).
结论:
- 深对高风险结肠直肠癌 (CRC) 群体的检测率特别高.
- 生活方式和饮食因素与深高风险人口的CRC风险密切相关.
- 针对这些可修改的风险因素的个性化干预和综合战略对于预防和控制CRC至关重要.
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