在日本使用保险索赔数据调查与药物相关的老年综合征
Sho Hasegawa1,2, Fumihiro Mizokami2,3, Tomohiro Mizuno1
1Department of Pharmacotherapeutics and Informatics, Fujita Health University, Toyoake, Japan.
Geriatrics & gerontology international
|December 12, 2023
概括
在日本,服用某些药物的老年人患有老年综合征 (GS) 更有可能经历处方级联. 食欲受损是与这种药物相关的连锁链接的常见症状.
科学领域:
- 老年学是指老年学的学科.
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 老年综合征 (GS) 在老年人中很常见,药物治疗通常是导致的因素.
- 与日本老年人药物相关的GS的具体原因尚不清楚.
- 了解药物的作用对于老年人群中GS的管理至关重要.
研究的目的:
- 调查日本老年门诊患者可能处方级联的速度.
- 要区分老年综合征 (GS) 和与药物相关的GS (GSAM).
- 确定与GSAM相关的趋势和风险因素.
主要方法:
- 对来自日本门诊患者的医疗保险索赔数据的回顾性分析 (2018年10月 - 2019年3月).
- 不包括住院患者.
- 基于药物使用的GS和可能GSAM (p-GSAM) 组的分类,并进行统计分析 (P < 0.05).
主要成果:
- 分析了超过137,000名门诊患者;GS组的7,342名和p-GSAM组的8,347名.
- 在p-GSAM组中,处方的平均数量显著更高 (P < 0.01).
- 胃口受损是p-GSAM组中最常见的症状 (P < 0.01),有33.9%的怀疑处方级联率.
结论:
- 服用GS引起的药物的患者的食欲受损可能会导致处方级联.
- 这些发现突出了药物使用与老年人处方级联之间潜在的联系.
- 建议进行进一步的研究,以制定预防这种级联的策略.
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