燃烧口腔疾病和胃食道逆流疾病之间的关系:一个范围审查
Linman Li1, Shuangshuang Wu1, Noboru Noma2
1Department of Oral Medicine, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.
Oral diseases
|December 12, 2023
概括
这篇评论探讨了口腔炎和胃食道逆流疾病之间的联系. 有证据表明可能存在关联,但需要更多的研究来证实这种联系.
科学领域:
- 胃肠道学和口腔医学
- 医学研究方法学 医学研究方法学
背景情况:
- 燃烧口腔疾病 (BMD) 是一种复杂的口腔疾病,病因不明.
- 胃食道逆流性疾病 (GERD) 是一种常见的胃肠道疾病,已知有食道外表现.
研究的目的:
- 进行范围审查,以探索口腔炎和胃食道逆流疾病之间的潜在关联.
- 综合现有的关于BMD和GERD之间患病率和关系的文献.
主要方法:
- 在多个数据库 (PubMed,EMBASE,Web of Science,Cochrane Library,Ovid,Scopus,EBSCOhost) 进行了全面的文献搜索,截至2023年8月22日.
- 对2795个记录的选发现了18项相关研究,包括横截面,病例控制,病例报告,病例系列和实验设计.
主要成果:
- 在BMD患者中,GERD的患病率从3.39%到23.4%不等,报告的喉回流率为50%-93.8%.
- 在9%-45%的GERD患者中报告了口腔灼热症状.
- 病例控制研究表明, BMD 患者的 GERD 患病率较高,并且病例系列显示用抗逆流疗法缓解症状.
结论:
- 目前的文献表明,口腔炎和胃食道逆流症之间存在潜在的相关性.
- 需要进一步进行高质量的研究,以确定联系并阐明潜在的机制,如pH值变化和唾液变化.
相关概念视频
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