一个可穿戴设备的视角在多发性硬化症中残疾进展的标准定义
Gloria Dalla Costa1, Carlos Nos2, Ana Zabalza2
1Vita-Salute San Raffaele University, Milan, Italy.
概括
可穿戴设备提供了多发性硬化症 (MS) 残疾进展的敏感,客观的跟踪. 持续的活动监测,就像每天的步骤一样,在检测标准临床量表中错过的微妙变化方面表现有希望.
科学领域:
- 神经学 神经学
- 生物医学工程 生物医学工程
- 数字健康数字健康
背景情况:
- 多发性硬化症 (MS) 是年轻人残疾的主要原因.
- 标准的临床尺度可能无法捕捉访问之间的微妙残疾变化.
- 需要针对多发性硬化症残疾进展采取客观,细致的措施.
研究的目的:
- 调查可穿戴设备数据是否提供更详细和客观的MS残疾进展指标.
- 探索持续活动监测在MS患者管理中的实用性.
主要方法:
- 中枢神经系统疾病的疾病和复发的远程评估 (RADAR-CNS) 研究招募了400名多发性硬化症患者.
- 对患者进行了24个月的临床评估 (EDSS,6MWT,T25FW) 和Fitbit数据的跟踪.
- 使用已建立的临床尺度来评估残疾进展情况.
主要成果:
- 在306名完成者中,74人显示残疾进展 (EDSS).
- 患有EDSS进展的患者每天步数比稳定的患者少1392步.
- 在进展和稳定的患者之间没有观察到随着时间的推移而减少步骤的显著差异,类似于6MWT和T25FW结果.
结论:
- 通过可穿戴设备的持续活动监测显示出作为MS残疾的敏感和生态有效措施的潜力.
- 可穿戴数据可以补充追踪多发性硬化症进展的传统方法.
- 需要进一步的研究来完善MS临床实践中可穿戴数据的使用.
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