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相关概念视频

Bipolar Disorder01:30

Bipolar Disorder

67
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
67
Theoretical Approaches to Psychological Disorder01:29

Theoretical Approaches to Psychological Disorder

229
The development of psychological disorders, which are characterized by deviant, maladaptive, and personally distressing behaviors, has been explored through several theoretical approaches.
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
229
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

102
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
102
Dissociative Identity Disorder01:30

Dissociative Identity Disorder

120
Dissociative Identity Disorder (DID), previously termed multiple personality disorder, is a complex psychological condition characterized by the presence of two or more distinct identities or personality states. Each identity exhibits unique patterns of behavior, voice, and mannerisms and may possess separate memories and emotional responses. The alternating control between identities can result in memory gaps and challenges in recalling daily activities, often exacerbating the individual's...
120
Diagnostic and Statistical Manual of Mental Disorders (DSM)01:27

Diagnostic and Statistical Manual of Mental Disorders (DSM)

57
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
57
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

677
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
677

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相关实验视频

Updated: Jul 8, 2025

Developing a Rat Model for Bipolar Disorder
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Developing a Rat Model for Bipolar Disorder

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284

在三个主要的精神疾病中,动态的结构-功能合.

Zhe Zhang1,2,3, Wei Wei1,4,5,6, Sujie Wang1

  • 1Department of Biomedical Engineering, & Department of Neurobiology, Key Laboratory for Biomedical Engineering of Ministry of Education, Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University, Hangzhou, China.

Psychological medicine
|December 12, 2023
PubMed
概括
此摘要是机器生成的。

这项研究揭示了大脑结构功能合在主要抑郁症,双相情感障碍和精神分裂症的共同和独特的改变. 这些发现为这些精神疾病的神经发育基础提供了洞察力.

关键词:
双相情感障碍是双相情感障碍的一种疾病.大脑网络 大脑网络认知缺陷 认知缺陷动态状态 动态状态 动态状态疾病特定的疾病.大型抑郁症主要是抑郁症.神经发育的神经发育精神疾病 精神疾病 精神疾病富人俱乐部组织组织.精神分裂症是一种精神分裂症.结构功能合 合这是一个跨诊断的跨诊断.

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Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
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Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
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相关实验视频

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Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
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科学领域:

  • 神经科学是一个神经科学.
  • 精神疾病 精神疾病
  • 大脑网络分析 脑网络分析

背景情况:

  • 非典型的大脑结构-功能关系与主要精神疾病有关.
  • 了解主要抑郁症 (MDD),双相情感障碍 (BD) 和精神分裂症 (SZ) 等疾病中这些模式的共同点和差异至关重要,但在很大程度上是未知的.

研究的目的:

  • 调查跨MDD,BD和SZ的共同和独特的动态结构-功能合模式.
  • 探索这些动态合模式如何与大脑网络拓学和信息处理有关.

主要方法:

  • 在452名患者 (MDD/BD/SZ) 和205名对照患者的量化动态结构-功能合在全球,中等和局部大脑网络层面.
  • 与功能网络拓特征相关的动态结构-功能合,以评估信息通信.

主要成果:

  • 动态结构-功能合在全球范围内在各种疾病中得到保护.
  • 在中级的富人俱乐部组织中,共享的异常与疾病的严重程度有关.
  • 在视觉,认知控制和默认模式网络中观察到本地级别的变化,显示了共享和独特的变化.

结论:

  • 研究结果表明,大规模大脑网络中的动态结构功能关系中存在跨诊断性和疾病特异性的变化.
  • 这些结果为精神疾病的神经发育基础提供了新的见解,并提出了潜在的生物标志物.