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Updated: Jul 8, 2025

Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota
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从分子动力学模拟中理解抑制机制,模拟多种类黄和依赖质子的葡萄糖载体之间的相互作用

Xianyang Zeng1, Risong Na2, Lianjuan Yang3

  • 1School of Chemistry, Institute of Theoretical Chemistry, Jilin University, Changchun, China.

Journal of biomolecular structure & dynamics
|December 12, 2023
PubMed
概括

黄类抑制剂通过与葡萄糖部位结合来阻断葡萄糖载体,在质子状态下表现出更好的疗效. 非抑制剂无法结合,这凸显了药物开发中占用场所的重要性.

关键词:
分子动力学分子动力学黄类化合物 黄类化合物葡萄糖/H + 同载体蛋白质复星醇是一种复星醇.

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