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多任务生物试验预培训对蛋白质 - 配体结合亲缘关系的预测

Jiaxian Yan1, Zhaofeng Ye2, Ziyi Yang2

  • 1Anhui Province Key Lab of Big Data Analysis and Application, University of Science and Technology of China, JinZhai Road, 230026, Anhui, China.

Briefings in bioinformatics
|December 12, 2023
PubMed
概括

这项研究引入了多任务生物测试预训 (MBP),这是预测蛋白质 - 配体结合亲和力 (PLBA) 的新框架. MBP利用具有多种亲和度标签的大型数据集来改善药物发现中的模型概括性.

关键词:
生物测试生物测试图表神经网络的神经网络预先培训的培训前培训蛋白联体结合亲和关系 蛋白联体结合亲和关系

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