一个由发育控制的细胞分解过程执行了Arabidopsis根盖的细胞死亡程序
Jie Wang1,2, Norbert Bollier1,2, Rafael Andrade Buono1,2
1Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent 9052, Belgium.
The Plant cell
|December 12, 2023
概括
植物编程细胞死亡 (PCD) 涉及特定的离子流和选择性分解,由Arabidopsis根盖中的SOMBRERO转录因子主导. 中央真空球分解是一个晚期的事件,与和酸化信号细胞死亡.
科学领域:
- 植物生物学 植物生物学
- 细胞生物学 细胞生物学
- 分子生物学分子生物学
背景情况:
- 编程细胞死亡 (PCD) 对多细胞真核生物至关重要,但其在植物中的执行比在动物中的理解要少.
- 阿拉比多普西斯的根盖提供了一个可处理的系统来研究发育性PCD.
研究的目的:
- 为了可视化和详细描述Arabidopsis根盖细胞中发育控制PCD期间的细胞事件.
- 确定关键的分子参与者和参与植物PCD执行的信号事件.
主要方法:
- 实时成像阿拉比多普西斯根盖细胞经历PCD.
- 使用光报道器来检测离子流和器官完整性.
- 研究NAC转录因子SOMBRERO的作用.
主要成果:
- PCD执行涉及选择性分解和离子流,由SOMBRERO编排.
- 细胞内的增加和酸性化先于真空分离,并触发细胞死亡.
- 线粒体,核和ER光膜释放蛋白质,而血膜对蛋白质保持完整.
结论:
- 植物中发育的PCD与动物的亡有机学的相似之处,特别是在离子流和膜完整性方面.
- 和酸化在末端分化的植物细胞中起到特定的PCD触发信号的作用.
- 这项研究为未来对植物PCD分子机制的研究提供了详细的细胞框架.
更多相关视频
12:01Long-term, High-resolution Confocal Time Lapse Imaging of Arabidopsis Cotyledon Epidermis during Germination
Published on: December 31, 2012
13.9K
09:41Translating Ribosome Affinity Purification TRAP to Investigate Arabidopsis thaliana Root Development at a Cell Type-Specific Scale
Published on: May 14, 2020
12.1K
相关概念视频
Overview of Cell Death
7.3K
Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the...
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the...
7.3K
The Cell Cycle Control System
3.0K
The cell cycle regulation directs how a cell proceeds from one phase to the next and begins mitosis. The cell cycle control system includes intracellular regulatory molecules and external triggers. They provide "stop" or "advance" signals and operate at specific cell cycle stages termed checkpoints to ensure that a particular process is completed before the cell advances to the next phase.
Cyclins and cyclin-dependent kinases (Cdks) are the primary cell cycle regulators and...
Cyclins and cyclin-dependent kinases (Cdks) are the primary cell cycle regulators and...
3.0K
Morphogenesis
28.2K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
28.2K
Apoptosis
11.5K
Apoptosis is a combination of two Greek words, 'apo' and 'ptosis,' meaning separation and falling off, respectively. Hippocrates used this word to describe gangrene, which was caused due to bandaging of fractured bones. Apoptosis was distinguished from necrosis in 1970 when John Kerr reported observations of morphological changes occurring during apoptosis. During one experiment, he observed that the disruption of blood supply to the liver tissue resulted in a size...
11.5K
Cell Signaling in Plants
5.6K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
5.6K
Autophagic Cell Death
3.4K
Christian de Duve discovered “autophagy,” a process in which cellular components are engulfed by membrane-bound organelles called autophagosomes. The autophagosomes then fuse with lysosomes to digest the enclosed contents. Autophagy is generally activated in cells to prevent cell death. However, cell death is triggered when the damage is beyond repair.
Autophagy and Apoptosis
Autophagy can activate apoptosis. In normal conditions, the autophagy activating protein Beclin-1 and...
Autophagy and Apoptosis
Autophagy can activate apoptosis. In normal conditions, the autophagy activating protein Beclin-1 and...
3.4K
