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使用磁共振成像-超声波融合的前列腺癌风险分层与系统的前列腺活检对比
Ghazal Khajir1, Benjamin Press1, Soum Lokeshwar1
1Department of Urology, Yale School of Medicine, New Haven, CT, USA.
JNCI cancer spectrum
|December 12, 2023
概括
磁共振成像-超声波融合向活检 (MRF-TB) 与单独的系统活检相比,稍微改变了前列腺癌风险分类. 虽然大多数患者仍处于类似的风险组,但很小一部分患者的积极监测资格可能会因MRF-TB而改变.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 图像引导前列腺活检技术提高了诊断的准确性.
- 磁共振成像-超声波融合向活检 (MRF-TB) 越来越多地使用.
- MRF-TB对临床风险分层的影响需要进一步调查.
研究的目的:
- 为了比较国家综合癌症网络 (NCCN) 来自MRF-TB的风险分组与单独的系统活检.
- 评估MRF-TB对前列腺癌风险评估和积极监测资格的影响.
主要方法:
- 在2017年1月至2021年7月期间接受MRF-TB的713名患者的回顾性分析.
- 在MRF-TB (系统性+向性) 和单独的系统活检之间对NCCN风险组分布的比较.
主要成果:
- 仅通过系统活检,就有28.7%的患者被归类为非常低或低风险患者,而MRF-TB被归类为26.6%.
- 一小部分 (4.6%) 的活检被重新分类为MRF-TB的高风险或非常高风险.
- MRF-TB可能会改变前列腺癌患者的一个子集的积极监测资格.
结论:
- 将MRF-TB添加到系统活检中可能会影响少数前列腺癌病例的积极监测资格.
- 建议对风险分组进行定量风险评估,以便在局部性前列腺癌管理中更准确地做出决定.
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