在患有阻塞性睡眠呼吸暂停综合征的儿童和青少年中分析QRS复杂形态
Elnur Gasimov1, Başak Yılmaz2, Gülçin Benbir Şenel3
1Department of Pediatrics, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
European journal of pediatrics
|December 12, 2023
概括
儿童的阻塞性睡眠呼吸暂停综合征 (OSAS) 与较低的QRS电压和在心电图上更分散的QRS模式有关. 这些发现表明,在患有OSAS的年轻患者中,心脏电气和结构变化发生了变化.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 睡眠医学 睡眠医学
- 心血管电生理学 心血管电生理学
背景情况:
- 儿科阻塞性睡眠呼吸暂停综合征 (OSAS) 与心血管并发症有关,原因是间歇性低氧化,高头,睡眠碎片化和交感激活.
- 未经治疗的OSAS可能会导致显著的心血管,神经,代谢和神经认知问题,可能涉及心脏导电系统.
研究的目的:
- 研究OSAS与儿童和青少年心脏导电系统的变化之间的关系.
- 为了确定特定的心电图变化表明心脏重塑在儿科OSAS患者.
主要方法:
- 使用夜间多睡眠学 (PSG) 诊断出OSAS的儿童的评估.
- 详细的心电图分析,包括最大空间向量大小 (QRSmax),电轴 (EA),心室缩和碎片化QRS (fQRS) 或隙波.
- 17名患有OSAS的男孩和13名健康的对照男孩之间的ECG参数的比较.
主要成果:
- 与对照组相比,患有OSAS的患者在V5衍生品的QRSmax和QRSmax平均值显著降低.
- 在OSAS组中,碎片化QRS (fQRS) 或划痕的R或S波的发生率显著更高,特别是在5岁以下的儿童中.
- 一个患有OSAS的男孩在心电图上显示了右心室缩;在任何一组中都没有观察到显著的左心室缩.
结论:
- 患有OSAS的男性儿童和青少年表现出明显的QRS复杂变化,包括降低QRS电压和增加fQRS频率.
- 这些心电图发现表明,OSAS显著影响心肌电气和结构改造,导致心室变化和儿科患者的心室内导电障碍.
- 观察到的变化在患有OSAS的年轻儿童中更为明显,突出显示了心肌发育的脆弱性.
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