慢性阻塞性肺病和心血管疾病:机械联系和对实践的影响
Tetsuro Maeda1, Mark T Dransfield
1Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Current opinion in pulmonary medicine
|December 12, 2023
概括
慢性阻塞性肺病 (COPD) 和心血管疾病 (CVD) 经常同时存在,影响患者的治疗结果. 了解它们的复杂相互作用对于改善临床护理和开发有针对性的干预措施至关重要.
科学领域:
- 肺部医学 肺部医学
- 心脏病学 心脏病学
- 内部医学 内部医学
背景情况:
- 慢性阻塞性肺病 (COPD) 和心血管疾病 (CVD) 是普遍存在的,往往是与严重的医疗负担并存的疾病.
- 人们越来越认识到COPD和CVD之间的相互作用的机制联系和临床影响.
- 在COPD患者中,心血管疾病的高患病率和反之亦然,以及恶化的结局一直被观察到.
研究的目的:
- 审查COPD和心血管疾病之间的机制联系.
- 为了突出其共存的临床影响.
- 讨论当前的理解和未来的方向在管理两个条件的患者.
主要方法:
- 关于COPD和CVD的最新科学文献的审查.
- 分析连接肺和心脏病理生物学的机械路径.
- 评估临床研究的患病率,结果和恶化风险.
主要成果:
- 慢性肺炎通过炎症,自主功能障碍和机械肺部影响对心血管系统产生负面影响.
- 在COPD患者中,心血管疾病的高患病率导致结果恶化,反之亦然.
- 慢性肺炎恶化显著增加心血管事件的风险.
- 现实世界的数据表明,并发性慢性肺炎和心血管疾病的管理不足.
结论:
- 慢性肺炎和心血管疾病之间的相互关系是复杂的,需要进一步的机制研究.
- 通过持续的研究来确定更好的治疗点是必不可少的.
- 需要加强医疗专业教育和新的查协议,以改善这些患者的临床护理.
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