淋巴瘤的全球负担:来自2019年全球疾病负担研究的估计
1Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, 230032, China.
Public health
|December 12, 2023
概括
全球淋巴瘤负担显示死亡率下降,但患病率增加,非霍奇金淋巴瘤发病率上升. 霍奇金淋巴瘤发病率整体下降,但根据地区和社会人口统计指数存在差异. 预防和精确的治疗非常重要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 淋巴瘤,包括霍奇金淋巴瘤 (HL) 和非霍奇金淋巴瘤 (NHL),代表了一个重要的全球健康问题.
- 了解长期的流行病学趋势对于有效的公共卫生战略和资源配置至关重要.
研究的目的:
- 从1990年到2019年划出淋巴瘤发病率,流行率和死亡率的全球趋势.
- 分析淋巴瘤的负担,包括失去了生命年 (YLLs) 和根据残疾调整的生命年 (DALYs),按社会人口统计指数 (SDI) 和全球地区分层.
主要方法:
- 利用了2019年全球疾病负担研究的数据.
- 针对HL和NHL的发病率,流行率,死亡率,YLLs,残疾生活年 (YLDs) 和DALYs的计算年龄标准化率.
- 按SDI和21个世界地区估计的年度百分比变化和分层分析.
主要成果:
- 2019年,NHL的发病率和流行率高于HL,但HL的死亡率更高.
- 全球HL发病率下降,而NHL发病率在1999年至2019年之间增加. 这两种疾病的患病率都增加了,而死亡率却下降了.
- 在不同SDI地区观察到发病率和死亡率趋势的显著变化,大多数地区的NHL发病率和死亡率显著增加,所有SDI水平的HL和NHL的患病率增加.
结论:
- 淋巴瘤在全球范围内仍然是一个重大的公共卫生挑战.
- 虽然死亡率有所下降,但患病率的增加和特定的区域趋势凸显了持续研究和干预的必要性.
- 加强预防策略,精确的诊断方法和先进的治疗干预措施对于管理全球淋巴瘤负担至关重要.
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