对出血时间的批判性重新评估
R P Channing Rodgers1,2, Jack Levin1,2
1Department of Laboratory Medicine, School of Medicine, University of California, San Francisco, California.
Seminars in thrombosis and hemostasis
|December 12, 2023
概括
出血时间测试是评估出血障碍的历史方法,涉及到皮肤切口的时间. 本次审查重新评估了其诊断实用性和历史修改.
科学领域:
- 血液学 血液学 血液学
- 临床病理学 临床病理学
背景情况:
- 流血时间测试,首次描述于1901年,是评估血液静止的一个历史性的方法.
- 许多修改,包括广泛使用的常春藤出血时间,已经开发出标准化程序.
- 该测试已被提出用于诊断血小板疾病,监测治疗,并预测出血风险.
研究的目的:
- 为了提供对出血时间测试的全面审查.
- 分析出血时间测试的历史发展和应用.
主要方法:
- 1990年进行了一项文献搜索,发现了讨论出血时间的862份文件.
- 该审查侧重于出血时间测试的演变和修改.
主要成果:
- 血液流血时间测试已被提出用于诊断血小板疾病,评估治疗疗效,并预测出血.
- 常见的方法是Ivy方法,涉及前臂切口和控制的静脉压力,是一种常见的变体.
结论:
- 从历史上看,出血时间测试在评估血液静止和血小板功能方面具有重要意义.
- 尽管有局限性,但该测试已被用于血液疾病的诊断和预后目的.
- 这次复刊提供了对基本血静评估工具的历史视角.
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