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Updated: Jul 8, 2025

Analyzing Craniofacial Morphogenesis in Zebrafish Using 4D Confocal Microscopy
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Analyzing Craniofacial Morphogenesis in Zebrafish Using 4D Confocal Microscopy

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由于骨质母细胞分化失败,Sc5d的损失导致了微骨

Chihiro Iwaya1, Akiko Suzuki1, Junichi Iwata2

  • 1Department of Diagnostic & Biomedical Sciences, The University of Texas Health Science Center at Houston, School of Dentistry, Houston, TX 77054, USA; Center for Craniofacial Research, The University of Texas Health Science Center at Houston, School of Dentistry, Houston, TX 77054, USA.

Journal of advanced research
|December 12, 2023
PubMed
概括

胆固醇合成缺陷通过扰乱骨质母细胞分化,在小鼠中引起下腔低成形. 这与初级毛功能受损和关键骨发育的信号通路有关.

关键词:
胆固醇的新陈代谢头骨面部骨的形成下的低成形情况主要的眼是主要的.在Sc5dd中,我们得到了sc5d.

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Notch Signaling Pathway03:14

Notch Signaling Pathway

The Notch signaling pathway is a major intracellular signaling pathway that is highly conserved over a broad spectrum of metazoan species. It stands unique from other intracellular signaling mechanisms in animals because notch protein itself acts as the receptor as well as the primary signaling molecule.
The Notch gene came into the limelight in 1914 after the discovery that its mutation in Drosophila melanogaster leads to a serrated (or "notched") wing margin phenotype. It was not...
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