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人类胰腺小岛内表观遗传变化的基因会影响线粒体功能,胰岛素分泌和2型糖尿病

Tina Rönn1, Jones K Ofori1, Alexander Perfilyev1

  • 1Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Scania University Hospital, Malmö, Sweden.

Nature communications
|December 12, 2023
PubMed
概括

胰腺小岛的表观遗传变化与2型糖尿病 (T2D) 有关. DNA甲基化变化影响胰岛素分泌和线粒体功能,这表明在T2D发育中发挥了作用.

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