对抗原特异性免疫耐受性的治疗诱导
Jessica E Kenison1, Nikolas A Stevens1, Francisco J Quintana2,3
1Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Nature reviews. Immunology
|December 12, 2023
概括
诱导持久的免疫耐受性对于治疗自身免疫性疾病,过敏和移植排斥至关重要. 本综述探讨了免疫耐受机制和临床应用的新治疗策略.
科学领域:
- 免疫学和翻译医学
背景情况:
- 对抗原特异性免疫耐受性的治疗诱导是管理自身免疫,过敏,器官移植和基因疗法的重要未满足的临床需求.
- 了解免疫耐受机制是开发新型治疗策略的关键.
结论:
- 了解免疫耐受性的进展为治疗免疫相关疾病提供了有希望的新途径.
- 开发强大,持久和抗原特异性免疫耐受性疗法对于临床进展至关重要.
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