胆病的临床相关性在经过皮肤内镜胃口术的患者中
Boram Cha1, Jungnam Lee1, Jaehyuk Lee1
1Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Republic of Korea.
Scientific reports
|December 12, 2023
概括
低体力活动和卧床状态是经过皮肤内镜胃口术 (PEG) 的患者胆结石的关键危险因素. 升高的C-反应蛋白 (CRP) 也会增加风险,这表明有针对性的查和预防.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
- 老年病的医生 老年病的医生
背景情况:
- 胆结石 (胆结石) 与减少体力活动有关.
- 人口老龄化导致更多的卧床患者需要穿皮内镜胃口术 (PEG).
- 在接受PEG手术的患者中经常观察到胆结石.
研究的目的:
- 在经过PEG插入的成年人中识别胆病的危险因素.
- 评估患者特征与PEG后胆结石形成之间的相关性.
主要方法:
- 在1996年3月至2021年12月接受PEG治疗的576名患者进行了回顾性单一中心研究.
- 分析变量包括年龄,性别,BMI,PEG指示,体力活动和实验室发现.
- 使用学生的t测试和千平方测试进行统计分析,以比较组.
主要成果:
- 在576名患者中,有161名患者 (28.0%) 发展为胆固醇.
- 确定了独立的危险因素:C-反应蛋白 (CRP) 的升高和身体活动的减少 (卧床状态).
- 卧床患者的胆病发病率为30.7%;体重指数和总胆固醇与胆结石大小相关.
结论:
- 减少体力活动,特别是卧床状态,是PEG患者胆结石的重要危险因素.
- 在PEG插入时初始CRP水平升高与胆结石风险增加有关.
- 建议在卧床患者中进行腹部成像和预防措施,患者的CRP水平高,接受PEG.
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