相关实验视频
Updated: Jul 8, 2025
08:53
Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
Published on: May 25, 2022
3.9K
在接受生育治疗的非生育人口中的细菌性阴道炎:一个前性队列研究
Marjolein M van den Tweel1,2, Ellen H A van den Munckhof3, Moniek van der Zanden2
1Department of Obstetrics and Gynecology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.
Journal of assisted reproduction and genetics
|December 12, 2023
概括
细菌性阴道炎 (BV) 在生育治疗中没有显著影响怀孕成功. 然而,BV可能会增加流产的风险,这需要在不育种群中进行进一步的研究.
科学领域:
- 生殖生物学和微生物学.
- 产科和妇科 产科和妇科
背景情况:
- 细菌性阴道炎 (BV) 与诸如早产等不良产科结果有关.
- 关于BV对生育治疗和不育妇女的影响的研究有限.
- 以前的研究表明,它对生育能力有负面影响,特别是在体外受精中.
研究的目的:
- 调查细菌性阴道炎与接受生育治疗的女性怀孕率之间的关联.
- 探索 BV 对子宫内授精,体外受精和细胞质内精子注射结果的影响.
主要方法:
- 76对夫妇进行了133次试图进行生育治疗的前性观察研究.
- 用qPCR和16S rRNA基因测序分析BV的阴道样本.
- 逻辑回归与通用估计方程用于分析数据,调整混因素.
主要成果:
- 在26%的样本中检测到细菌性阴道炎.
- 根据BV状态,持续怀孕或活产率没有显著差异.
- 在BV的妇女中观察到流产率增加的趋势.
- 在基线BV阳性参与者中观察到更高的BMI和吸烟率.
结论:
- 在生育治疗中,细菌性阴道炎似乎没有显著影响正在进行的怀孕率.
- BV可能与流产风险增加有关.
- 需要进一步的研究来澄清BV在生育干预后流产中的作用.
相关概念视频
01:28Infertility in Females
311
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
311
01:24In Vitro Fertilization
284
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
284