复发性复发性多发性硬化症患者的冲动性和注意力缺陷-多动性症状:一个病例控制研究
Hacer Akgül Ceyhun1, Nuray Bilge2, Duygu Değirmencioğlu Gök1
1Department of Psychiatry, Ataturk University School of Medicine, Erzurum, Turkey.
Neurological research
|December 13, 2023
概括
患有复发性缓解性多发性硬化症 (RRMS) 的患者表现出更高的注意力缺陷症状和认知功能障碍,影响他们的生活质量. 干预措施应专注于预防抑郁症和增强RRMS患者的认知储备.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 自免疫性疾病 自免疫性疾病
背景情况:
- 多发性硬化症 (MS) 是一种进展性,自身免疫性,神经退行性疾病.
- 自身免疫性疾病与注意力缺陷多动性障碍 (ADHD) 的发病有关.
研究的目的:
- 评估患有复发性复发性多发性硬化症 (pwRRMS) 的患者的ADHD症状.
主要方法:
- 48名RRMS患者和54名对照人完成了自我报告问卷 (BDI,A-ADHD,BIS-11,WHOQoL-Bref) 和认知测试 (SCWT).
- 精神病医生使用Stroop颜色和词语干扰测试 (SCWT) 评估认知功能.
- 疲劳严重程度尺度 (FSS) 和扩展残疾状态尺度 (EDSS) 评估了RRMS患者.
主要成果:
- 与对照组相比,PwRRMS在SCWT子测试中显示了显著更高的注意力缺陷得分和较差的表现.
- 注意力缺陷得分与MS持续时间正相关,与MS诊断年龄负相关.
- 认知功能障碍和抑郁症状在pWRRMS中负面预测了生活质量.
结论:
- 认知功能障碍,包括注意力缺陷和冲动性,降低了 pwRRMS 的生活质量.
- 实施预防抑郁症和增强认知储备的计划对于管理RRMS影响至关重要.
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