对患有长期Covid综合征的儿童进行肺功能评估
Francesco Sansone1, Paola Di Filippo1, Daniele Russo1
1Department of Pediatrics, Pediatric Allergy and Pulmonology Unit, University of Chieti-Pescara, Chieti, Italy.
Pediatric pulmonology
|December 13, 2023
概括
长期Covid综合征 (LCS) 在儿童中更常见于老年儿童,但与无症状同龄人相比,肺功能或超声检查结果没有差异. 在LCS儿童中较低的FeNO水平可能表明潜在的标志物.
科学领域:
- 儿科肺病学 儿科肺病学
- 传染性疾病 传染性疾病
- 呼吸系统医学 呼吸系统医学
背景情况:
- 持续的COVID-19后症状,称为长期Covid综合征 (LCS),影响儿童,病理生理机制不明.
- 了解儿童的LCS对于识别潜在原因和潜在诊断标志物至关重要.
研究的目的:
- 为了比较患有LCS的儿童和无症状的COVID-19幸存者之间的肺功能和肺超声波 (LUS) 模式.
- 在儿科患者中探索肺功能,LUS发现和LCS之间的关联.
主要方法:
- 58名儿童 (5-17岁) 的前性观察研究:28名患有LCS和30名无症状对照.
- 评估包括螺旋测量,身体囊造影,DLCO,部分呼出的氧化 (FeNO) 和肺超声波 (LUS).
- 收集关于人口统计,病史和急性COVID-19症状的数据.
主要成果:
- 患有LCS的儿童年龄较大,报告有更多的疲劳,咳,运动不耐受和呼吸障碍.
- 两组之间没有发现肺功能 (精神计量,DLCO) 或LUS异常的显著差异.
- 患有LCS的儿童表现出较低的FeNO值,但LCS和异常肺功能或LUS之间没有发现联系.
结论:
- 在儿童中,LCS似乎在老年人群中更为普遍.
- 肺功能和结构在患有LCS的儿童和无症状同龄人之间没有显著差异.
- 患有LCS的儿童中较低的FeNO水平表明其作为生物标志物的潜在实用性,需要进一步调查.
相关概念视频
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
01:17Pulmonary Cycle: Exhalation
1.6K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.6K
01:29Pneumonia II: Pathophysiology
283
The pathophysiology of pneumonia involves the following steps:
283
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K
01:23Assessment of Respiration
1.1K
The respiratory system's basic structures and primary functions lay the foundation for nurses' comprehensive respiratory assessments. This assessment includes subjective and objective data to gauge the patient's respiratory health.
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
1.1K
01:27Physical Assessment of the Respiratory Tract II: Inspection
300
Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles.
Chest Configuration
The chest configuration...
Chest Configuration
The chest configuration...
300