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Updated: Jul 8, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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基于基结构搜索的小分子设计,用于在结直肠癌中抑制CDK-2

Uchechukwu C Ogbodo1, Sofela Salimat2, Damilola S Bodun3

  • 1Department of Applied Biochemistry, Faculty of Biosciences, Nnamdi Azikiwe University, Awka, Nigeria.

Journal of biomolecular structure & dynamics
|December 13, 2023
PubMed
概括

研究人员从类似于安东的分子中确定了潜在的CDK2抑制剂,用于结直肠癌药物发现. 这些化合物显示出有前途的结合亲和力和生物活性,需要进一步研究.

关键词:
在CDK2中使用CDK2.结肠直肠癌是一种癌症.模拟MD的模拟方法安托西安尼尼 (anthocyanin) 是一种在的中.

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