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Updated: Jul 8, 2025

An Immunofluorescent Method for Characterization of Barrett’s Esophagus Cells
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WATS 3D:在胃肠道病理学家中对巴雷特食道相关性发育不良的观察者间研究

Deepa T Patil1, John R Goldblum2, Gregory Lauwers3

  • 1Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Clinical and translational gastroenterology
|December 13, 2023
PubMed
概括

胃肠道病理学家可以在短时间的培训后使用广域体样本 (WATS 3D) 准确诊断巴雷特食道形,显示出优秀的观察者间一致性和高诊断信心.

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Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
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Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
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The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
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