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双胞胎与单独的早产产后的反复出现的早产:一个回顾性队列队列

Tamar Wainstock¹, Ilana Shoham-Vardi¹, Ruslan Sergienko¹

¹Department of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

|December 13, 2023

概括

在双胞胎怀孕中经历过早产 (PTD) 的女性,与单独怀孕PTD的女性相比,复发PTD的风险较低. 这一发现有助于理解PTD复发风险因素.

科学领域:

产科和妇科产科和妇科
围产儿医学围产儿医学
生殖健康生殖健康

背景情况:

过早分娩 (PTD) 的病史是随后PTD的主要风险因素.
了解影响PTD复发的因素对于改善围产期结果至关重要.

研究的目的:

为了比较从双胞胎怀孕与单独怀孕中患有PTD史的女性中复发PTD的风险.

主要方法:

一项以人口为基础的回顾性队列研究分析了连续两次怀孕的妇女,其中第一个导致PTD.
在双胞胎和单身指数怀孕中比较了PTD复发发病率.
多变量后勤模型评估了双胞胎状态和PTD复发之间的关联,考虑到妊娠年龄,妊娠间隔和受孕模式.

主要成果:

该研究包括15590名女性;10.8%的怀孕是双胞胎指数,89.2%的怀孕是单子指数.
在双胞胎PTD后的女性中,复发性PTD发生在10.5%的女性中,而单独PTD后的女性则为21.9% (aOR=0.50,95%CI 0.32-0.76).
这些发现在各种分层中保持一致,包括妊娠间隔,妊娠年龄和受孕模式.

结论:

双胞胎怀孕中有PTD病史的女性,与单独怀孕的女性相比,出现复发PTD的风险较低.
这表明,双胞胎和单胎怀孕之间,PTD的潜在机制或管理可能会有所不同.

关键词:

多重怀孕多重怀孕的时间过早分娩过早分娩经常发生的早产.一个回顾性队列队列.

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