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Updated: Jun 20, 2026

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使用死后毒理测试计划检测到的与雪拉相关的死亡病例的定性和定量特征

Varun Vohra1, Gabrielle K Stroh-Steiner2, Prentiss Jones3

  • 1Department of Emergency Medicine, Michigan Poison & Drug Information Center, Wayne State University School of Medicine, Detroit, MI, USA.

Clinical toxicology (Philadelphia, Pa.)
|December 13, 2023
PubMed
概括

密歇根州的过量死亡中越来越多地发现了西拉,通常与芬太尼混合. 纳洛的使用率很低,这凸显了需要更广泛的获取和分发,以应对日益增加的毒品死亡人数.

关键词:
克西拉 (Xylazine) 是一种这是一种阿片类阿片类药物.在死后进行尸检.毒理学 毒理学 毒理学

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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...