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一个高灵敏度低纳米流量LC-MS配置,用于高通量样本限制蛋白质学

Runsheng Zheng1, Manuel Matzinger2, Rupert L Mayer2

  • 1Thermo Fisher Scientific, Dornier Str. 4, 82110 Germering, Germany.

Analytical chemistry
|December 13, 2023
PubMed
概括

本研究介绍了蛋白质组学高通量纳米LC-MS方法,优化了像单细胞蛋白质组学 (SCP) 这样的样本有限分析的灵敏度和速度. 开发的工作流提高了蛋白质组覆盖率和吞吐量,使最小的生物样本能够有效分析.

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