评估使用自动化健康计划数据识别乳腺癌复发的算法
Erin J Aiello Bowles1, Candyce H Kroenke2, Jessica Chubak1
1Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, Washington.
概括
我们使用行政数据改进了检测乳腺癌复发的方法. 结合算法增强了正预测值 (PPV) 以识别没有额外的手动审查的复发.
科学领域:
- 在瘤学瘤学.
- 生物统计学 生物统计学
- 医疗信息学 医疗信息学
背景情况:
- 使用行政数据检测乳腺癌复发的更新算法.
- 扩展了以前开发的方法,以提高准确性.
研究的目的:
- 验证对算法对单个算法进行重复识别.
- 评估结合算法性能与手动抽象的对比.
主要方法:
- 生成的算法组合:高特异性/PPV和高灵敏性.
- 将算法结果与600名患者手动抽象的结果进行比较 (乳腺癌I-IIIA阶段,2004-2015年).
- 使用考克斯回归来分析复发率的风险因素.
主要成果:
- 高特异性/PPV组合:98%的特异性,72%的PPV,64%的灵敏度.
- 高灵敏度组合:特异性为83%,PPV为29%,灵敏度为80%.
- 结合的算法为大多数风险因素产生了类似的复发率.
结论:
- 结合算法改善了乳腺癌复发检测的积极预测值 (PPV).
- 在使用组合算法时,不需要对不一致记录进行额外的审查.
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