为了实现跨国研究伙伴关系的公平:在低收入和中等收入国家实施适应性平台试验的经验教训
Chelsea Modlin1,2, Jeremy Sugarman1,3,4, Gershom Chongwe5
1Berman Institute for Bioethics, Johns Hopkins University, Baltimore, MD, 21205, USA.
Wellcome open research
|December 13, 2023
概括
针对COVID-19的自适应平台试验增加了,特别是在跨国合作伙伴关系的LMIC中. 确保这些研究合作中的公平性对于公平的全球健康结果至关重要.
科学领域:
- 全球健康 全球健康
- 临床试验 临床试验
- 流行病学 流行病学
背景情况:
- 在COVID-19大流行期间,自适应平台试验迅速扩大.
- 在LMICs和HICs之间的跨国研究伙伴关系促进了试验实施.
- 合作伙伴关系的公平性对于解决全球卫生研究中LMIC缺点至关重要.
研究的目的:
- 在适应性平台试验中确定研究伙伴关系公平性的关键考虑因素.
- 检查跨国COVID-19试验中的公平维度.
主要方法:
- 进行了非正式的文献评论.
- 与跨国COVID-19适应性平台试验的领导者进行了讨论.
- 考量被组织成八个主题类别.
主要成果:
- 确定了八个主题类别:认识体系结构,资金,道德和监管监督,领导,审判后访问,知识翻译和能力建设.
- 适应性平台试验对伙伴关系公平提出了独特的挑战和考虑.
- 程序性和实质性公平措施对于全球卫生研究至关重要.
结论:
- 这些发现为建立公平的跨国全球健康研究伙伴关系提供了见解.
- 专注于伙伴关系公平对于全球卫生倡议的成功和公平至关重要.
- 加强LMIC研究能力和确保公平的利益分享是关键成果.
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