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在低资源环境中,母亲的极端年龄和不良妊娠结果

Paul Nyongesa¹, Osayame A Ekhaguere², Irene Marete³

¹Department of Obstetrics and Gynecology, Moi University School of Medicine, Eldoret, Kenya.

Frontiers in global women's health

|December 13, 2023

概括

青春期母亲 (<20岁) 和晚年母亲 (AMA,>35岁) 的怀孕与低收入和中等收入国家的母亲,围产和新生儿死亡率的风险更高有关.

科学领域:

产科和妇科产科和妇科
孕产妇和儿童的健康
全球健康全球健康

背景情况:

青少年和晚年孕妇的怀孕带来了重大风险,特别是在低收入和中等收入国家 (LMICs),负担很高的不良结果.
由于这些年龄组对母亲和儿童健康的影响不成比例,因此对这些年龄组进行批判性审查至关重要.

研究的目的:

为了确定青少年和晚年母亲年龄怀孕的患病率.
分析六个LMIC中与这些母亲年龄极端相关的不良妊娠结果 (母体,围产,新生儿).

主要方法:

对从2010年至2020年前性收集的数据进行历史队列分析.
包括来自六个国家的孕妇和新生儿:刚果民主共和国,危地马拉,印度,肯尼亚,巴基斯坦和赞比亚.
普森回归模型用于计算不利结果的调整相对风险 (aRR),将年龄组与20-24岁的参考年龄组进行比较.

主要成果:

分析了超过60万次分娩;13%是青少年,5%是晚年孕产妇 (AMA).
随着年龄的增长,孕产妇死亡率 (MMR) 增加:青少年为83/100,000,AMA为298/100,000.
AMA与2.55倍更高的孕产妇死亡风险相关;青少年和AMA怀孕都与增加的围产和新生儿死亡率相关.

结论:

在LMIC中观察到高的孕产妇死亡率,随着孕产妇年龄的增加而升级.
晚期孕产妇年龄 (AMA) 显著增加孕产妇死亡风险;AMA和青少年怀孕都会增加围产死亡风险.
这些不良结果模式在研究的LMIC中显示了最小的区域差异.

关键词:

青少年怀孕中的青少年怀孕先进的孕产妇年龄怀孕怀孕低收入和中等收入国家.孕产妇死亡率的比率新生儿死亡率新生儿死亡率怀孕的结果.

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