计算流体动力学模拟用于评估生物实验室暴露的空间可变性和最佳通风场景
Susan Caskey1, Clifford K Ho1, LouAnn C Burnett1
1Sandia National Laboratories, Albuquerque, New Mexico, USA.
概括
计算流体动力学 (CFD) 建模有助于评估生物安全级别2 (BSL-2) 实验室的风险. 优化空气流和通风位置可以显著减少潜在的工人暴露在空气中的污染物中.
科学领域:
- 职业健康和安全 职业健康和安全
- 空气动力学和流体力学.
- 生物安全工程 生物安全工程
背景情况:
- 在生物安全级别2 (BSL-2) 实验室中,人类对生物材料的暴露存在不确定性.
- 计算流体动力学 (CFD) 提供了一种模拟和理解暴露风险的方法.
研究的目的:
- 在BSL-2实验室使用CFD模拟空气中的污染物度.
- 评估不同实验室配置对潜在工人暴露的影响.
主要方法:
- 使用CFD模型在实际的BSL-2实验室环境中模拟污染物分散.
- 分析了各种通风,采样和源位置的配置.
主要成果:
- 通风,取样和来源位置显著影响空气中的污染物度和暴露水平.
- 污染物羽毛的行为根据来源和空气流动模式变化了数量级.
- 靠近排气口和通过流的条件是封闭羽毛的关键因素.
结论:
- 建议设计BSL-2房间以最大限度地提高排气口的通道流量,并最大限度地减少分散.
- CFD模拟是优化实验室设计,通风位置和传感器定位的宝贵工具.
- 差价合约可以提高BSL-2设施中潜在风险的表征和监测.
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