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直接说一句:针对性地将mRNA传递给免疫细胞,以改善疫苗设计

Bruna Clemente1, Maxime Denis1, Camila Pedroso Silveira1

  • 1GSK, Siena, Italy.

Frontiers in immunology
|December 13, 2023
PubMed
概括

针对免疫细胞,特别是树突细胞 (DCs) 的抗原增强了疫苗的效力. 在先进的疫苗开发中,基于纳米粒子的mRNA传递系统正在探索有效的细胞特异抗原向.

关键词:
在C型乳清中,C型的乳清含有树突细胞是一种树突细胞.脂质纳米颗粒的使用方法这是mRNA疫苗.有针对性的交付目标.

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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