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共同路径光学连贯性断层扫描引导的垂直肺切割用于DALK.

Yaning Wang1, Shoujing Guo1, Justin D Opfermann2

  • 1Electrical and Computer Engineering, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, USA.

Proceedings of SPIE--the International Society for Optical Engineering
|December 13, 2023
PubMed
概括

一种新的光学连贯断层扫描 (OCT) 传感器集成管 (VIREC) 能够精确地对Descemet的膜 (DM) 进行气动剖析. 这种手术工具被证明是有效的产生"大气泡"的技术在深前面状角膜成形 (DALK).

关键词:
达尔克 (DALK) 是一个达尔克.光学连贯性断层扫描仪远距离的光学传感器

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科学领域:

  • 眼科医生 眼科 眼科
  • 手术创新 在外科创新.
  • 医疗器械 医疗器械

背景情况:

  • 深前面状角膜整形术 (DALK) 是一种手术程序,用于替换患病的角膜层.
  • 精确切割Descemet的膜 (DM) 对于成功的DALK至关重要.
  • 目前用于DM剖析的方法可能具有挑战性,并存在穿孔的风险.

研究的目的:

  • 设计和评估一种新型的光学连贯性断层扫描 (OCT) 传感器集成的27度垂直插入剃须刀边管 (VIREC).
  • 评估VIREC在从角膜层切割出Descemet膜 (DM) 的气动剖析中的疗效.
  • 确定VIREC是否适合在DALK中促进"大气泡"技术.

主要方法:

  • 开发一个包含OCT传感器的VIREC设备,用于实时可视化.
  • 在ex vivo牛 (N=5) 和子 (N=5) 角膜上进行的外科手术.
  • 将VIREC垂直插入到DM附近的所需深度,用于气动剖析.

主要成果:

  • 在牛角膜中,成功地清洁了树叶层的剖析,没有树叶白化.
  • 在所有没有穿孔的牛眼睛测试中,一致生成"大气泡".
  • 在子眼中观察微泡,表明了特定物种的反应.

结论:

  • 该VIREC设备显示了作为气动DM剖析的有效手术工具的潜力.
  • 维雷克促进了"大气泡"技术,这是DALK程序的关键步骤.
  • 进一步的研究可能会探索VIREC在活体DALK手术中的应用.