结构化的软颗粒物物质用于将生物活性化合物输送到食品中,并在结肠中发挥作用
Qixin Zhong1, Fatima Reyes-Jurado1, Kriza Faye Calumba1
1Department of Food Science, University of Tennessee, Knoxville, TN, USA. qzhong@utk.edu.
Soft matter
|December 13, 2023
概括
软颗粒物 (SPMs) 是一种有前途的方法,可以将生物活性化合物 (BCs) 输送到肠道. 在加工和消化过程中,SPM保护BCs,提高其改善肠道健康的有效性.
科学领域:
- 食品科学与技术 食品科学与技术
- 营养科学 营养科学
- 生物技术是生物技术.
背景情况:
- 为肠道健康提供生物活性化合物 (BCs) 面临着挑战,因为在加工和消化过程中会降解.
- 软颗粒物 (SPMs) 正在成为BCs的有效载体,保护其生物活性并提高生物可用性.
- 目前的战略重点是通过整合BC特性来优化SPM设计,以克服生物可用性限制.
研究的目的:
- 审查利用SPMs向肠道输送BC的挑战,前景和需求.
- 探索SPM的设计原则,以增强BC封装和有针对性的交付.
- 讨论在功能性食品中实施基于SPM的输送系统的实际考虑.
主要方法:
- 对SPM和BC传递系统的现有文献的审查.
- 对影响SPM设计的物理,化学和生物特性进行分析.
- 在SPM制造中考虑食品级材料,成本,可持续性和可扩展性.
- 评估SPM对食品质量的影响以及功能性食品对健康的益处.
主要成果:
- SPM可以有效地捕捉BCs,通过加工,储存和消化来保持其生物活性.
- 根据BC特征量身定制SPM属性,可以提高输送到结肠的效果.
- 食品级分子和可扩展的制造工艺是实际SPM开发的关键.
- 包含SPM的功能性食品的成本效益和已证明的健康益处需要进一步验证.
结论:
- SPM代表了一种可行的策略,可以提高BCs对肠道健康的交付和有效性.
- 在SPM设计中整合BC特性,以及可持续制造,对于成功应用至关重要.
- 需要进一步的研究来确认健康益处,并优化SPM在功能性食品中的整合.
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