在患有下痢症的个体中,所有原因和特定原因死亡率
David Mataix-Cols1,2, Kayoko Isomura1, Anna Sidorchuk1
1Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet and Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
患有下痢症 (健康焦虑障碍) 的人面临着明显更高的死亡风险. 这包括自然死亡人数的增加和与普通人口相比,自杀的风险特别高.
科学领域:
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 抑郁症或健康焦虑障碍是一种常见的精神疾病,往往被诊断不足.
- 患有下痢症的个体会持续担心患有严重疾病.
- 与阴性二合一症相关的死亡风险尚未得到充分确立.
研究的目的:
- 确定一大群被诊断患有阴极症的个体的全因和因特定死亡率.
- 为了比较患有和不患有阴性病的个体之间的死亡风险.
主要方法:
- 瑞典一项全国性匹配队列研究包括4,129名经ICD-10验证的患有下痢症的个人和41,290名对照人.
- 关于死亡率的数据来自瑞典死亡原因登记册.
- 用分层的Cox比例危险回归模型来分析死亡风险,调整社会人口统计学因素和精神病相关疾病.
主要成果:
- 患有下痢症的个体的原始死亡率为每1000人年8.5,对照组为5.5.
- 经过调整后的分析显示,在下症组中,全因死亡率 (HR,1.69) 的风险增加.
- 这包括自然 (HR, 1.60) 和非自然原因 (HR, 2.43) 的更高风险,自杀是显著的贡献者 (HR, 4.14).
结论:
- 患有下痢症的个体具有较高的自然和非自然原因死亡风险,特别是自杀.
- 这些发现强调了改善对健康焦虑障碍的检测和获得基于证据的护理的需要.
- 优先考虑对患有下痢症的人群的心理健康支持,对于降低死亡率至关重要.
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