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骨转移患者的生活质量问题:系统性审查
Thenugaa Rajeswaran1, Henry C Y Wong2, Elwyn Zhang1
1Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.
概括
骨转移患者的生活质量是复杂的,包括身体,功能和心理健康. 目前的评估工具错过了新疗法的新出现的问题,需要更新以捕捉完整的患者体验.
科学领域:
- 在瘤学瘤学.
- 抚慰性护理是一种缓解性护理.
- 患者报告的结果
背景情况:
- 骨转移 (BM) 影响30-75%的晚期癌症患者,显著影响生活质量 (QoL).
- 有许多患者报告的结果工具用于评估BM中的QoL,但它们的全面性正在审查中.
- 了解QOL对于评估治疗方法和改善转移性骨病患者护理至关重要.
研究的目的:
- 系统地审查和列出与骨转移 (BM) 以及其干预有关的生活质量 (QoL) 问题.
- 确定在BM患者群体中使用的常见QoL评估工具.
- 确定现有评估工具未充分解决的质量质量问题.
主要方法:
- 在Ovid MEDLINE,EMBASE和Cochrane控制试验中央注册表中进行了全面的文献搜索.
- 关键词包括"骨转移"",生活质量"和"患者报告的结果".
- 数据提取集中在特定的QOL问题和原始研究研究中使用的工具上.
主要成果:
- 在BM中普遍存在的QoL问题包括疼痛,行走障碍,疲劳和心理困扰 (无助,抑郁,焦虑).
- 这些症状会对社会互动和日常生活产生负面影响.
- 新的BM治疗引入了未解决的QoL问题,如疼痛爆发,类似流感的症状和药物诱导的骨髓缩 (下疼痛).
结论:
- 骨转移治疗的进步扩大了患者经历的QoL问题的范围.
- 现有的QOL评估工具可能无法充分捕捉当代治疗方法的全部影响.
- 对新发现的,与治疗有关的QOL问题进行前性验证是必要的,以便将其整合到当前的评估工具中.
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