哈洛佩里多尔在美国的引入:一个失败的试验及其后果的故事
João Tavares1,2
1Unidade de Alcoologia de Lisboa, DICAD, ARSLVT, Lisbon, Portugal.
Journal of the history of the neurosciences
|December 13, 2023
概括
哈洛佩里多尔 (Haloperidol) 是一种的药物.
科学领域:
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
- 医学史 医学史 医学史
背景情况:
- 哈洛佩里多尔 (Haloperidol) 是一个开创性的布蒂罗芬神经麻药,于1958年在欧洲开发出来.
- 它的欧洲引入受到热烈欢迎,但进入美国市场面临重大挑战.
- 曼哈顿的一项关键临床试验与美国利的商业失败有关.
研究的目的:
- 为了重建曼哈顿临床试验的故事,为了haloperidol.
- 调查欧洲与美国对利的不同接收背后的原因.
- 探索社会因素的影响,包括性别和种族,对试验的结果和halooperidol的轨迹.
主要方法:
- 曼哈顿审判历史的重建.
- 分析与试验相关的发表论文和采访.
- 检查社会对药物的接收和精神病学实践的影响.
主要成果:
- 曼哈顿审判的结果与欧洲大陆的结果形成鲜明对比.
- 这种差异显著影响了大西洋两岸的利的市场存在.
- 试验的结果可能影响了精神病学经验和理论框架.
结论:
- 在haloperidol的接收中,大西洋裂受到临床数据和社会文化因素的复杂相互作用的影响.
- 了解这一历史事件,可以让我们深入了解精神病治疗和研究的背景.
- 社会动态,包括性别和种族,在塑造哈洛皮里多的不同结果和看法方面发挥了作用.
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