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Updated: Jul 8, 2025

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单分子阵列 (SIMOA) 的进步,用于超灵敏地检测生物分子

Renkai Dong1, Ning Yi1, Dechen Jiang1

  • 1State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.

Talanta
|December 13, 2023
PubMed
概括

单分子阵列 (SIMOA) 技术使得癌症和COVID-19等疾病的生物标志物的超敏感检测成为可能. 这种数字方法实现了原子的灵敏度,推进了医疗诊断和监测.

关键词:
数字ELISA是一个数字ELISA.微波电池阵列中的微波电池.单个分子检测检测 单个分子检测超敏感的 超敏感的

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
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