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黑白差异在子宫癌症状和诊断时的阶段

Xiao Xu¹, Ling Chen², Marcella Nunez-Smith³

¹Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT, United States of America; Yale Cancer Outcomes, Public Policy and Effectiveness Research (COPPER) Center, Yale School of Medicine, New Haven, CT, United States of America; Department of Obstetrics and Gynecology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States of America.

Gynecologic oncology

|December 13, 2023

概括

患有子宫癌的黑人患者更频繁地出现非绝经后出血 (PMB) 症状,这些症状与晚期诊断有关. 这些症状差异导致子宫癌分期的种族差异.

科学领域:

在瘤学瘤学.
流行病学流行病学
健康差异在健康上的差异

背景情况:

子宫癌的诊断和分期可能会受到患者人口统计学和症状呈现的影响.
癌症结局中的种族差异凸显了需要调查促成因素,如症状差异.

研究的目的:

为了调查子宫癌的症状是否在黑人和白人患者之间有所不同.
确定这些症状差异如何影响子宫癌诊断阶段.

主要方法:

利用监测,流行病学和最终结果-医疗保险数据库 (2008-2017) 对2328名黑人和21774名白人的子宫癌患者.
将预诊断症状分为单独的绝经后出血 (PMB),PMB与其他症状,单独的非PMB症状或没有症状.
通过回归模型分析了种族,症状表现和晚期诊断之间的关联.

主要成果:

与白人患者相比,黑人患者更经常出现PMB加其他症状 (63.1%对58.0%) 或单独非PMB症状 (13.1%对9.4%).
黑人患者有更高的未调整的晚期诊断风险 (45.0%vs30.3%).
症状的差异部分解释了晚期诊断的种族差异,非PMB症状与风险增加密切相关.

结论:

在诊断时,非绝经后出血症状与更先进的子宫癌阶段有关.
黑人患者中非PMB症状的更高患病率可能导致诊断延迟和晚期阶段化.
解决症状识别和评估差异对于改善黑人患者子宫癌结果至关重要.

关键词:

黑色黑色黑色早期诊断早期诊断早期诊断种族差异是种族差异.一个阶段,一个阶段.症状症状症状症状这是子宫癌的原因.

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