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Updated: Jul 8, 2025

In Vitro Assay to Evaluate the Impact of Immunoregulatory Pathways on HIV-specific CD4 T Cell Effector Function
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Chi3l1:T细胞封锁中的新人

Mi He1, Marleen Kok1

  • 1Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, the Netherlands.

Immunity
|December 13, 2023
PubMed
概括

瘤细胞分泌Chi3-like 1 (Chi3l1),一种细胞因子,通过中性粒细胞外细胞陷 (NET) 形成驱动T细胞排斥. 耗尽Chi3l1增强T细胞透,并改善对PD-1阻断免疫疗法的反应.

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