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Updated: Jul 8, 2025

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来自iPSC的低免疫性组织常存记忆T细胞介导强大的抗瘤活性,对抗宫癌

Yoshiki Furukawa1, Midori Ishii1, Jun Ando2

  • 1Department of Hematology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.

Cell reports. Medicine
|December 13, 2023
PubMed
概括

针对人类乳头瘤病毒 (HPV) 的工程T细胞显示出对宫癌治疗的希望. 修改后的T细胞逃避免疫排斥,提供了潜在的"现成"疗法.

关键词:
在CRISPR-Cas9无痕基因编辑中.编辑的HLA类I编辑的iPSCs.宫癌:子宫癌是一种癌症.人类乳头瘤病毒特定的CTLs.低免疫性iPSC衍生的CTLs复兴的CTLs已经恢复了年轻.一个单细胞RNA测序.组织内存T细胞是组织内存T细胞.基因编辑的两个步骤.现货 CTL治疗疗法

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