一个多中心随机对照试验的设计,比较共享决策与动机面试的有效性,以及自愿阿片类药物逐渐减少的认知行为疗法:INSPIRE研究协议
Mark J Edlund1, Sonia M Thomas1, Laura K Wagner1
1RTI International, Research Triangle Park, NC, United States.
Contemporary clinical trials
|December 13, 2023
概括
本试验将共享决策与其他治疗方法进行比较,用于慢性疼痛患者的阿片类药物剂量逐渐减少. 研究结果将为减少阿片类药物处方和增强疼痛管理的策略提供信息.
科学领域:
- 疼痛管理 疼痛管理
- 临床试验 临床试验
- 行为健康 行为健康
背景情况:
- 研究长期阿片类药物治疗中患有慢性非癌症疼痛的成年人的阿片类药物逐渐减少.
- 专注于疼痛综合服务:有效减少疼痛的干预措施 (INSPIRE) 试验.
- 涉及成年人每天至少服用20个MME治疗慢性非癌症疼痛.
研究的目的:
- 评估共享决策与动机面试以及慢性疼痛的认知行为疗法.
- 评估对自愿阿片类药物剂量逐渐减少的干预措施的比较有效性.
- 为减少阿片类药物处方和改善慢性疼痛管理提供证据.
主要方法:
- 在三个学术健康中心实用,多中心,随机试验.
- 参与者随机分配到共享决策或MI+CBT进行慢性疼痛干预.
- 主要结局:12个月后每日处方阿片类药物的剂量发生变化;次要结局:疼痛干扰和身体功能.
主要成果:
- (根据提供的摘要,结果尚未提供)
结论:
- 这项试验的结果将指导临床医生,研究人员和政策制定者.
- 旨在为减少阿片类药物处方的战略提供信息.
- 旨在通过基于证据的干预措施改善慢性疼痛的管理.
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